The manufacturing layer for designed proteins.
Designed proteins are faster to generate than they are to make.
The systems we currently have to manufacture proteins are constraining what we can imagine and design them to do.
We close the gap between sequence and scale.

What we do
The proteins that will matter this decade will not be the ones evolution handed us. They will be designed, as much for how they are made as for what they do. The bottleneck is no longer design. It is manufacturing.
Change Bio is building the platform that closes that gap. We make designed proteins at bioreactor scale, generate the data that makes manufacturability predictable, and license the know-how to produce the winners.
The arc
Every designed protein follows the same arc. We work at every stage.
Design
Make manufacturability a first-class concern from the first sequence. Build and screen libraries in K. phaffii in your own lab.
nsure platformPrototype
Send us a sequence. We return a usable protein sample, made under industrially representative conditions, in weeks.
Rapid prototypingScale
Licensing for operators producing designed proteins at industrial scale.
Licensing
Why us
Bioreactor first
Every sample is produced under industrially representative conditions.
Data driven
We generate manufacturability data, not just protein.
Designed to scale
A direct route from prototype to production.
Supported by